I think my speakers should be closer together than they are and with less toe-in. I did replace my monitor a couple months ago and didn’t have the big monitor in the middle, but a 24″ next to me. I didn’t really notice much difference.
My room pic is attached, it is about 16’x30′ room opening to kitchen then dining room. speakers are about 5′ from back wall, one is 3″ from side wall.
Panels have a lot less room boundary issues than cone speakers. The biggest concern is having room behind the speaker.